polio vaccine line

Randomized Clinical Trials for Vaccine Safety, Efficacy and Effectiveness

Some of the misinformation regarding vaccines includes an argument that vaccines have not been tested against a saline placebo in a double-blinded randomized clinical trial. This misinformation is aimed at confusing the wealth of evidence regarding the safety and effectiveness of immunizations. In this blog post, we will explain what a blinded randomized clinical trial is, when this study design has been used in the development of immunizations, and why it is not used as often anymore.