Back in 1759, Benjamin Franklin wrote an introduction to a pamphlet aimed at encouraging people to get inoculated with smallpox in a controlled way in order to gain immunity and prevent epidemics. Before and after Benjamin Franklin’s time, social influencers have had great influence on whether or not people take action. Like Benjamin Franklin, Catherine The Great of Russia — then the ruler of the Russian Empire — also influenced her people to adopt variolation. Today, we have many more social influencers because of mass media, and public health agencies around the world who are looking to promote the COVID-19 vaccine have taken notice.